H Pylori Treatment Options Penicillin Allergic

Generally first line treatment may include one of the following regimens.

H pylori treatment options penicillin allergic. Resistance is a concern with a single antibiotic regimen. Bismuth quadruple therapy does not contain amoxicillin and may be used in truly penicillin allergic patients. Bismuth salt tetracycline and metronidazole plus a ppi bismuth. Pylori infected patients allergic to penicillin the generally recommended first line treatment with omeprazole clarithromycin and metronidazole has low efficacy for curing the infection.

Regimen is simple 2 tablets twice daily and well tolerated but requires 14 days of therapy. The conclusion of this study is that h. Rbc clarithromycin x 14 days is a second line option in patients who are not able to tolerate amoxicillin or metronidazole in ppi triple therapy regimens. Rescue options in these patients with penicillin allergy may include a regimen with rbc tetracycline and metronidazole.

1 amoxicillin is a key component in several h pylori therapies because resistance rates remain relatively low. Bismuth quadruple therapy is particularly attractive in patients with any previous macrolide exposure or who are allergic to penicillin strong recommendation. Bismuth quadruple therapy consisting of a ppi bismuth tetracycline and a nitroimidazole for 10 14 days is a recommended first line treatment option. Helicobacter pylori first line treatment and rescue option containing levofloxacin in patients allergic to penicillin in h.

Clarithromycin a proton pump inhibitor ppi and amoxicillin or metronidazole triple therapy. Pylori infected patients allergic to penicillin the generally recommended first line treatment with omeprazole clarithromycin and metronidazole has low efficacy for curing the infection. However there are alternatives. Low quality of evidence.

When should penicillin allergy testing be considered in patients with h. Literature suggests that most patients with a documented history of penicillin allergy do not have true hypersensitivity that would preclude the use of amoxicillin containing regimens. Pylori infected patients allergic to penicillin may be treated with a first line treatment combining ppi clarithromycin and metronidazole. Amoxicillin is an important component of h.

If a patient received a first line treatment containing clarithromycin bismuth quadruple therapy or levofloxacin salvage regimens are the preferred treatment options.