H Pylori Treatment Pcn Allergy

Helicobacter pylori eradication is a challenge in patients allergic to penicillin especially those who have failed a first eradication trial.

H pylori treatment pcn allergy. Pylori infection are outlined in the american college of gastroenterology acg guidelines which provide both first line and alternative therapies. Pylori infection is a common worldwide infection that is an important cause of peptic ulcer disease and gastric cancer. We treated a total of 28 patients allergic to penicillin with a proton pump inhibitor ppi metronidazole 250 mg bid and sitafloxacin 100 mg bid for one to two weeks. Prospective single centre study including 40 consecutive treatments administered to patients.

Amoxicillin is an important component of h. Since publication of the last american college of gastroenterology acg clinical guideline in 2007 significant scientific advances have been made regarding the management of h. Pylori in patients allergic to penicillin should be performed using regimens without penicillin derivatives. However there are alternatives.

Helicobacter pylori infection remains one of the most common chronic bacterial infections affecting humans. On the other hand a levofloxacin containing regimen together with omeprazole and clarithromycin repres. The most significant advances have been made in the arena of medical treatment. Infection with h pylori is associated with the development of peptic ulcer disease gastric cancer and mucosa associated lymphoid tissue lymphoma.

Pylori may also have a role in uninvestigated and functional dyspepsia ulcer risk in patients taking low dose aspirin or starting therapy with a non steroidal anti. To assess the efficacy and tolerability of h. Recommendations for the treatment of h. Helicobacter pylori infection is prevalent in about one half of the world s population.

When should penicillin allergy testing be considered in patients with h. Pylori first line treatment and rescue options in patients allergic to penicillin.